Goldenrod (Solidago virgaurea)

Traditional Indications

Goldenrod is anti-catarrhal, anthelmintic, anticoagulant, antifungal, anti-inflammatory, antiseptic, aromatic, astringent, carminative, diaphoretic, diuretic, febrifuge and stimulant. Goldenrod is one of the first plants to think of for upper respiratory catarrh, whether acute or chronic. It may be used in combination with other herbs in the treatment of influenza. According to Priest and Priest, Goldenrod is specific for influenza, repeated colds, catarrhal bronchitis with purulent expectoration, putrescent tonsillitis, naso-pharyngeal catarrh with sneezing and excessive mucus. Goldenrod is a safe and gentle remedy for a number of disorders. In particular, it is a valuable astringent remedy treating wounds and bleeding, whilst it is particularly useful in the treatment of urinary tract disorders, being used both for serious ailments such as nephritis and for more common problems such as cystitis. Goldenrod is specific for ear infections. (1)

Pharmacognosy

Goldenrod contains rutin and phenolic glycosides. (2) Phenolic glycosides are anti-inflammatory. (3) Rutin is used to treat capillary fragility,

The plant contains antifungal saponins. Solidago virgaurea water extract inhibits the Candida albicans yeast. (4) The candida fungus is the cause of vaginal and oral thrush.

Goldenrod contains antibacterial clerodane diterpenes. (5) Other active sontituents including protocatechuic acid (PC), chlorogenic acid (CA), and kaempferol-3-O-rutinoside (K-O-R) have been isolated from the Solidago virgaurea extract. (6)

A mouse model has indicated Goldenrod to be promising as an antineoplastic medicine with minimal toxicities. (7)

Goldenrod has displayed an anti-obesity effect through regulation of adipogenesis and lipogenesis pathways in high-fat diet-induced obese mice. (2)

 

1. PFAF. Solidago virgaurea. 2019.
2. Wang Z, Kim JH, Jang YS, Kim CH, Lee J-Y, Lim SS. Anti-obesity effect of Solidago virgaurea var. gigantea extract through regulation of adipogenesis and lipogenesis pathways in high-fat diet-induced obese mice (C57BL/6N). Food & nutrition research. 2017;61(1):1273479-.
3. Zhang L-J, Huang H-T, Huang S-Y, Lin Z-H, Shen C-C, Tsai W-J, et al. Antioxidant and Anti-Inflammatory Phenolic Glycosides from Clematis tashiroi. Journal of Natural Products. 2015;78(7):1586-92.
4. Chevalier M, Medioni E, Prêcheur I. Inhibition of Candida albicans yeast–hyphal transition and biofilm formation by Solidago virgaurea water extracts. 2012;61(7):1016-22.
5. Starks CM, Williams RB, Goering MG, O’Neil-Johnson M, Norman VL, Hu J-F, et al. Antibacterial clerodane diterpenes from Goldenrod (Solidago virgaurea). Phytochemistry. 2010;71(1):104-9.
6. Hwang SH, Kim JH, Wang Z, Lee J-Y, Lim SS. Analytical Method for the Validation of Three Polyphenols as a Marker Compound for the Standardization of Solidago virgaurea subsp. gigantea Extracts and Antiadipogenesis of Harvesting Time and Location. Journal of analytical methods in chemistry. 2017;2017:3047408-.
7. Gross SC, Goodarzi G, Watabe M, Bandyopadhyay S, Pai SK, Watabe K. Antineoplastic activity of Solidago virgaurea on prostatic tumor cells in an SCID mouse model. Nutrition and cancer. 2002;43(1):76-81.